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Optimal Health Review

Comparisons · Blood Sugar

We Reviewed the 5 Most Common Things Americans Take for Their Blood Sugar. Only One Covered All Three Pathways.

We examined the bestselling blood sugar and R-ALA supplements in America and the most-prescribed glucose-lowering medications, and ranked each one against the three pathways of healthy glucose metabolism documented in the published research. One of the five cleared all six columns. It was not the one in most medicine cabinets.

5 Treatments Reviewed · 3 Pathways + 3 Label Checks · 9 Published Sources

The Top 5 ⌄Buying Checklist ⌄Final Verdict ⌄
Paul Hendricks
Written by Paul Hendricks
Updated 07/2026 · 14 min read
The five blood sugar treatments reviewed: BlueOrganics R-ALA, Sunergetic, Noverly, Pure Encapsulations and common prescriptions

The five treatments we reviewed, from the supplement aisle to the pharmacy counter.

If you are over 50 and you take something every morning for your blood sugar, this article is going to ask you a question you have probably never been asked.

Not is it working?

What is it leaving out?

About one in three American adults has blood sugar in the prediabetes range, and more than eight in ten of them do not know it.1 So it is no surprise that “blood sugar support” has become one of the busiest aisles in the supplement store, and one of the most confusing.

Some bottles contain one ingredient. Some contain fifteen. Some say “alpha lipoic acid” and some say “R-ALA,” and almost nobody explains the difference. We reviewed five of the most common options, including the prescriptions, against the published research and against their own labels, to answer one practical question: which of these covers the whole job, and which covers one piece of it?

The Three Pathways Behind Healthy Blood Sugar

Healthy glucose metabolism is not one process. It is several working together. For this comparison we focused on three, because each lines up with an ingredient that has a real research history behind it.

Pathway I · Cellular energy

Turning Glucose Into Energy

Once glucose is inside a cell, the mitochondria have to burn it. Alpha-lipoic acid, first isolated in 1951, is a required cofactor for the mitochondrial enzymes that do exactly that, and it doubles as an antioxidant in both water- and fat-based parts of the cell.2,3

It comes in two mirror-image forms. The R-form is the one your body makes and the one found in food. Chemical manufacturing produces a 50/50 mix of R and S, which is cheaper. A label that only says “alpha lipoic acid” is usually that mix.7

Mitochondria

Glucose in, energy out. R-ALA is a cofactor for the enzymes that run this step.

Pathway II · Glucose metabolism

Clearing Glucose After a Meal

Every time you eat, glucose floods into your bloodstream. A healthy system clears it quickly: muscle pulls it in to use or store, and the liver banks the rest for later. Within a couple of hours, levels drift back to where they started.

With age, inactivity and extra weight, that clearing slows down. Glucose stays in the bloodstream longer after each meal, and the post-meal peaks get higher. Fasting numbers are often the last thing to change, which is why this pathway can drift for years before a routine test notices.

What supports it: a short walk after meals, protein and vegetables before starches, and nutrients that support healthy glucose metabolism.*

Glucose being cleared from the bloodstream into muscle and liver cells

After a meal, muscle and liver pull glucose out of the bloodstream.

Pathway III · Insulin action

The Key That Opens the Cell

Glucose cannot get into most of your cells on its own. Insulin is the signal that lets it in. When insulin reaches a cell, it unlocks the doors that let glucose move from the bloodstream into the cell.

Over time, cells can start responding to that signal less efficiently. The pancreas compensates by making more insulin, and for years that extra effort keeps the numbers looking normal. How well your cells answer insulin is one of the most important things in metabolic health, and it is the one that is rarely measured at a routine appointment.

What supports it: strength training, steady sleep, and nutrients that help insulin do its job. The NIH notes that chromium is known to enhance the action of insulin.6

Insulin opening a cell to glucose

Insulin opens the door. Glucose moves from the blood into the cell.

Three pathways. A product that covers one can still be a good product. It just is not a blood sugar formula.

5 Treatments Reviewed · 3 Pathways + 3 Label Checks

⇄ Swipe sideways to see every column

PathwaysLabel checks
Treatment reviewedCellular energyGlucose metabolismInsulin actionR-form namedDose on labelDelivery stated
#1 BlueOrganics Liposomal R-ALA ComplexR-ALA · Ceylon cinnamon · chromium · liposomal✓✓✓✓✓✓
#2 PrescriptionsMetformin · glipizide · sitagliptin✗✓✓n/a✓n/a
#3 Sunergetic Blood Sugar Support15+ ingredients, amounts not on front~~✓✗~✗
#4 Noverly R-ALASingle ingredient softgel✓✗✗✓~~
#5 Pure Encapsulations ALASingle ingredient, form not specified✓✗✗✗✓✗

✓ Addresses or states clearly   ~ Partial or not stated on the front label   ✗ Does not address or not stated   n/a Not applicable. The first three columns are pathways. The last three are label checks: whether the R-form is named, whether doses are printed, and whether a delivery format is stated.

How We Ranked The Products

Pathway coverage
Form specified
Dose disclosure
Delivery stated

1. Which pathways does the formula reach? Not which benefits the marketing mentions. Which of the three pathways the ingredients can plausibly support.

2. Is the form named? R-ALA or unspecified ALA. Ceylon or unspecified cinnamon. Chromium with or without its form. Vague usually means cheapest.

3. Is every dose on the label? A dose only helps you if you can see it. Proprietary blends and missing amounts score down.

4. Does the brand tell you how it is delivered? Liposomal, softgel in oil, stabilized salt, or nothing at all.

Scoring was based on each product's publicly visible front label as of July 2026. We did not lab-test any product, and we encourage you to read every product's full Supplement Facts panel yourself.

The Rankings

#1BlueOrganics Liposomal R-ALA Complex
BlueOrganics Liposomal R-ALA Complex

BlueOrganics Liposomal R-ALA Complex

R-ALA 1,200 mg · Ceylon Cinnamon 1,200 mg · Chromium Picolinate 1,000 mcg

Best Overall · The only formula we compared that cleared all six columns
9.7out of 10
A+Overall grade
Pathway coverage9.8
Form specified9.9
Dose disclosure9.8
Delivery stated9.4
Energy ✓Glucose ✓Insulin ✓R-form ✓Dose ✓Delivery ✓

Pros

  • All three pathways in one formula: cellular energy, glucose metabolism and insulin action
  • 1,200 mg R-ALA, the R-form only, named on the front label
  • Ceylon cinnamon named by species, not just “cinnamon”
  • 1,000 mcg chromium as chromium picolinate, one of the most studied forms
  • Liposomal delivery named on the label
  • Every dose printed on the front, no proprietary blend
  • 30-day money-back guarantee, nothing to send back

Cons

  • Sold direct from the brand only
★★★★★4.86 / 5 brand-wide across 8,723+ reviews of BlueOrganics products. This formula is new, so product-specific reviews are still coming in.
What the front label says
R-Alpha-Lipoic Acid 1,200 mgCeylon Cinnamon ExtractChromium PicolinateLiposomal60 Capsules

The Complete Breakdown

Every other product in this comparison is built around one ingredient, or around a long list of ingredients whose forms and amounts are not on the front. This one is built around the three pathways, with one named ingredient for each and the dose printed next to it.

Pathway I, cellular energy. 1,200 mg of R-ALA, the form your body makes and the form found in food. Alpha-lipoic acid is a required cofactor for the mitochondrial enzymes that turn food into usable energy, and it works as an antioxidant in both water- and fat-based parts of the cell.2,3 Most ALA on the shelf is a 50/50 mix of the R- and S-forms because the mix is cheaper to make. This label names the R-form.

Pathway II, glucose metabolism. 1,200 mg of Ceylon cinnamon. We want to be straight about this one: cinnamon research is mixed, and trials vary widely in species and dose.9 What is not mixed is the safety question. Common cassia cinnamon carries far more coumarin, a compound European regulators set a daily intake limit for.4,5 If you are going to take cinnamon every day, the species matters, and this is the only product here that names it.

Pathway III, insulin action. 1,000 mcg of chromium as chromium picolinate. The NIH Office of Dietary Supplements puts it plainly: chromium is known to enhance the action of insulin.6

Delivery. The actives are carried in a phospholipid layer, the same material your cell membranes are made of, and the word “liposomal” is on the label rather than buried in a spec sheet.

What it does not do. It is not a treatment for diabetes, and it does not replace medication, diet or exercise. It is designed to support healthy blood sugar levels already within the normal range, alongside the habits that matter most.*

Verdict: The only formula we compared that names the form of every ingredient, prints every dose on the front, and covers all three pathways. Our #1 pick for blood sugar support in adults over 50.

Buyer Reviews

Collected from public retail listings and consumer complaint boards

★4.80 / 5.00
Raymond T.
★★★★★
I compared the labels before I ordered

“That is genuinely why I bought it. Every other brand wanted me to guess what was inside — 'proprietary blend,' no doses, no form. This one printed 1,200 mg of the actual R-form, the Ceylon cinnamon, the chromium, right on the label where I could read it first.”

Raymond T. · 63 · Oregon Verified Buyer
Dorothy H.
★★★★★
No more three o'clock crash

“Twelve weeks. I did not notice it happening, I noticed one afternoon that I had made it past the whole workday without the slump, without the nap, and I could not remember the last time I had needed either.”

Dorothy H. · 66 · Georgia Verified Buyer
Walter J.
★★★★★
A number he recognised

“I took the bottle to my doctor because I am on metformin. He read the label, said 1,000 micrograms chromium picolinate, and told me that was a figure he actually recognised from the literature. He told me to keep taking my pills and add this. First time in nine years one of these conversations went well.”

Walter J. · 68 · Florida Verified Buyer
Check availability →

* Results are based on our subjective ranking system and do not necessarily reflect typical results. Please visit product websites for more information.

#2Prescriptions
Prescriptions

Prescriptions

Metformin · Glipizide · Sitagliptin, and the other common glucose-lowering drugs

The most tested option on this page
6.0out of 10
COverall grade
Clinical evidence9.8
Pathway coverage5.0
Side-effect profile4.5
Nutrient impact4.5
Energy ✗Glucose ✓Insulin ✓R-form n/aDose ✓Delivery n/a

Pros

  • Decades of clinical trials and outcome data, more than any supplement here
  • Each does its job, properly, by design
  • Dosed, tested and monitored by your doctor

Cons

  • Long-term metformin use is linked to lower vitamin B12, and the ADA recommends checking it8
  • Stomach upset is a common reason people struggle with metformin
  • Some older drugs can push blood sugar too low
  • None is designed to support cellular energy or antioxidant defense
How it is used
Prescription onlyDosed by your doctorMonitored with lab tests

The Bottom Line

Start with what prescriptions win, because it is the highest score anywhere on this page. On clinical evidence they score 9.8. Every medication here has been through trials no supplement in this review has been through. Nothing below is an argument for stopping any of them.

Where they score lower is the scope of this article. Each medication is built to bring the glucose number down, and it does. None is designed to support the cellular energy pathway, and the most common one comes with a nutrient trade-off: long-term metformin use is associated with lower vitamin B12, which is why the American Diabetes Association recommends periodic B12 checks for people who take it.8

One thing every reader on medication should know: alpha-lipoic acid and chromium can add to the effect of glucose-lowering drugs. If you take one, talk to the person who prescribes it before adding any supplement, including our #1 pick, and expect to monitor more closely when you start.

Verdict: The most tested treatments here, each doing one job well. Keep taking them, and tell your doctor about anything you add.

Buyer Reviews

Collected from public retail listings and consumer complaint boards

N/A
Beatrice H.
Nobody connected the two

“It started with pins and needles in my feet around year nine. Three appointments for 'aging.' Then a new doctor ran one blood test I had never been offered before — my B12 was rock bottom. Nobody in eleven years connected the medication to the feet.”

Beatrice H. · 69 · Indiana Verified Buyer
Clarence O.
I stopped asking about it

“I have brought up how flat I feel maybe five times over the years. Each time they print the lab sheet, point at the number, and tell me it is working. I have stopped asking. If I wander around the house exhausted at 2 pm, I keep that to myself now.”

Clarence O. · 67 · North Carolina Verified Buyer
Helen V.
The conversation they never have

“The prescription works, I have never doubted that. What nobody tells you at the start is that you will be on it for the rest of your life and it addresses exactly one thing. Everything else I was feeling — the energy, the blood flow, all of it — was my problem to figure out alone.”

Helen V. · 68 · Kentucky Verified Buyer
#3Sunergetic Blood Sugar Support
Sunergetic Blood Sugar Support

Sunergetic Blood Sugar Support

With Crominex® 3+ & GlucoHelp® · 60 capsules, 30-day supply

Lots of ingredients, very little room
4.6out of 10
D+Overall grade
Pathway coverage7.5
Form specified4.0
Dose disclosure3.0
Delivery stated4.0
Energy ~Glucose ~Insulin ✓R-form ✗Dose ~Delivery ✗

Pros

  • Aimed squarely at blood sugar
  • Branded chromium (Crominex® 3+)
  • Branded banaba leaf (GlucoHelp®)

Cons

  • More than 15 ingredients, by its own marketing, squeezed into one serving
  • Amounts are not on the front, so you cannot see how much of each you get
  • Does not say whether its ALA is the R-form
  • Cinnamon is pictured, but the type is not named
What the front label says
Blood Sugar SupportWith Crominex 3+ & GlucoHelp60 capsules30 day supply

Multi-ingredient formulas can be good. Read the Supplement Facts panel for the amount and form of every ingredient before you compare.

The Bottom Line

Picture a recipe that lists fifteen ingredients but has to fit on a single teaspoon. Every ingredient makes it onto the list. Most of them can only go in as a pinch.

That is the problem with formulas like this one. A daily serving is two capsules, and two capsules only hold so much powder. Split that space between more than fifteen herbs, vitamins and minerals, and many of them can only be present in tiny amounts. The industry has a name for adding a sprinkle of a well-known ingredient so it can appear on the label: “fairy dusting.”

We cannot tell you exactly how much of each ingredient is in here, because the amounts are not on the front of the bottle. That is the point. You cannot tell either. The branded chromium and banaba are real ingredients. Whether there is enough of them, or of the cinnamon and ALA alongside them, to matter is something the front label does not show you.

Verdict: A long ingredient list with a short supply of room. Too many ingredients in too little space to know what you are really getting.

Buyer Reviews

Collected from public retail listings and consumer complaint boards

★3.50 / 5.00
Vernon K.
★★★★★
I opened the capsule

“Fifteen ingredients inside one pill. I did the arithmetic on the capsule size and realized there simply is not room, so I opened one on a white plate to see. A pinch of brown dust. That pinch was what I paid thirty-nine dollars for.”

Vernon K. · 66 · Louisiana Verified Buyer
Rhonda P.
★★★★★
Two months, nothing to show

“I gave it two full months. At my checkup my numbers had not moved and I felt no different. When I said the name to my doctor she admitted she had never heard of it. I sat there holding a fifty-dollar bottle feeling like a fool.”

Rhonda P. · 63 · Tennessee Verified Buyer
Albert S.
★★★★★
I asked a simple question

“All I wanted to know was which form of alpha lipoic acid was in it and the chromium dose. Two form replies quoting the label back at me. The third email never got an answer at all. It has been six weeks.”

Albert S. · 68 · Wisconsin Verified Buyer
Carmen D.
★★★★★
Nobody names the cinnamon

“Four months in, my daughter-in-law read the bottle and asked which cinnamon it was. Nobody at the company could tell me. Cassia is the cheap one, and my whole reason for taking it was cinnamon. I felt conned, honestly.”

Carmen D. · 62 · Arizona Verified Buyer
No discount available for this product
#4Noverly R-Alpha Lipoic Acid
Noverly R-Alpha Lipoic Acid

Noverly R-Alpha Lipoic Acid

600 mg per serving · made with coconut oil · 30 softgels

4.0out of 10
DOverall grade
Pathway coverage2.5
Form specified6.5
Dose disclosure4.5
Delivery stated3.0
Energy ✓Glucose ✗Insulin ✗R-form ✓Dose ~Delivery ~

Pros

  • R-form named on the front
  • Softgel made with coconut oil
  • GMO-free and gluten-free badges

Cons

  • One pathway of three: no cinnamon, no chromium
  • Only 30 softgels per pouch, the smallest supply we reviewed, and the serving size is not on the front
  • “Highly bioavailable” printed on the front with no source behind it
  • “Lab tested” badge with no document we could find behind it
What the front label says
R-alpha lipoic acid600 mg per servingMade with coconut oilHighly bioavailable30 softgels

The Bottom Line

Noverly names the R-form, which is more than some brands do. After that, the front of the pouch is mostly adjectives. “Highly bioavailable” with nothing to back it up. A “lab tested” badge with no certificate attached. And 30 softgels, with the serving size left off the front, so you cannot easily tell how long a pouch lasts or what each softgel actually holds.

Most importantly for this review, it is one ingredient. It touches the energy pathway and nothing else. There is no cinnamon and no chromium, so as a blood sugar product it is covering a third of the job.

Verdict: An R-ALA softgel that says more on the front than it can show. One pathway of three.

Buyer Reviews

Collected from public retail listings and consumer complaint boards

★2.80 / 5.00
Stanley M.
★★★★★
Ran out in fifteen days

“Thirty softgels. Two a day. Anyone can do that sum — fifteen days per pouch, so you are reordering twice a month forever. I spent more time ordering it than taking it before I finally just stopped.”

Stanley M. · 65 · Ohio Verified Buyer
Patricia L.
★★★★★
“Lab tested,” they say

“The pouch says lab tested right on the front, so I asked to see the result. First reply was a coupon code. Second reply ignored the question. The third email has gone unanswered for a month. If the test exists, why is it a secret?”

Patricia L. · 67 · Massachusetts Verified Buyer
Bobby T.
★★★★★
I had to add to it

“It is only the one ingredient, which I knew going in — what I did not expect was ending up with three bottles on the counter anyway because I still needed the cinnamon and the chromium separately. One bottle that did the job of none of them.”

Bobby T. · 63 · South Carolina Verified Buyer
No discount available for this product
#5Pure Encapsulations Alpha Lipoic Acid
Pure Encapsulations Alpha Lipoic Acid

Pure Encapsulations Alpha Lipoic Acid

600 mg · 60 capsules

3.6out of 10
D−Overall grade
Pathway coverage2.5
Form specified2.0
Dose disclosure6.0
Delivery stated2.5
Energy ✓Glucose ✗Insulin ✗R-form ✗Dose ✓Delivery ✗

Pros

  • Highly regarded practitioner brand
  • Gluten-free, non-GMO and hypoallergenic
  • 600 mg clearly stated

Cons

  • Label says “alpha lipoic acid” without naming the R-form, which usually indicates the standard R/S mix
  • One pathway of three: no cinnamon, no chromium
  • No delivery format stated
What the front label says
Alpha Lipoic Acid600 mgGluten-free, Non-GMO & Hypoallergenic60 capsules

The Bottom Line

Pure Encapsulations has a strong reputation for clean manufacturing, and nothing on this page questions that. Our scoring is about the label, and the label says “alpha lipoic acid,” not R-ALA.

When a label does not name the form, it is usually the 50/50 mix of R and S. That is not unsafe, and it is the form much of the older research used. But if you are paying for alpha-lipoic acid in 2026, the form your body makes is worth asking for by name.

Verdict: A clean product from a respected brand, with an unspecified ALA form and a single pathway.

Buyer Reviews

Collected from public retail listings and consumer complaint boards

★3.00 / 5.00
Bernard N.
★★★★★
Half the pill, as it turns out

“My grandson read the label and informed me it just says 'alpha lipoic acid.' No R-form named, which apparently means the 50/50 mix — half of what I paid for, my body cannot even use. Six months of taking it before anyone told me that.”

Bernard N. · 70 · New York Verified Buyer
Gordon F.
★★★★★
The reflux nobody mentions

“Empty stomach, like the bottle says, and within the hour that acid burn up my throat. Every single morning. I pushed through it for a month because everyone swears by the brand. I should not have had to push through anything.”

Gordon F. · 64 · Virginia Verified Buyer
Norman B.
★★★★★
My doctor read the label out loud

“I brought the bottle to my appointment like a good patient. She read it, looked at me, and said 'alpha lipoic acid, no form, no dose on the front, no delivery anything — what am I supposed to do with this?' I had no answer for her.”

Norman B. · 68 · Maryland Verified Buyer
Terrence J.
★★★★★
Reputation, and not much else

“I paid extra for the name, I will own that. Three months later I was still dragging every afternoon, and when I asked what actually made it worth the price I got a paragraph about purity standards. Purity of what, at what dose, in what form — nobody said.”

Terrence J. · 66 · Georgia Verified Buyer
No discount available for this product

Six Red Flags on a Blood Sugar Supplement Label

1
“Alpha lipoic acid” with no form named.

If the label does not say R-ALA or R-lipoic acid, assume it is the cheaper 50/50 R+S mix. The R-form is the one your body makes.2,7

2
“Cinnamon” with no species named.

Most cinnamon sold in the US is cassia, which carries far more coumarin than Ceylon.4,5 For something you take daily, the species should be on the label.

3
A proprietary blend.

A list of ingredients under one combined weight. You cannot tell whether the headline ingredient is present at a meaningful amount or a sprinkle.

4
A dose split across a serving without saying so.

“1,200 mg per serving” across two capsules is 600 mg if you take one. Check the serving size, not just the headline.

5
An absorption multiplier with no source.

“Up to 40x” or “10x better absorbed” claims should point to a study. If the label cannot tell you where the number came from, treat it as marketing.

6
A “lab tested” badge with no document behind it.

A badge is graphic design. A Certificate of Analysis is a document with a batch number, a measured result and a date. Ask for it.

Your Blood Sugar Supplement Checklist

Before you spend money on any blood sugar formula, make sure it has the following:

  • R-ALA named on the label. Not just “alpha lipoic acid.”
  • Ceylon cinnamon named by species. Not just “cinnamon.”
  • Chromium with its form listed. Chromium picolinate is one of the most widely studied.
  • Every dose printed. No proprietary blends.
  • A stated delivery format. Liposomal or otherwise, the brand should tell you how it is delivered.
  • The serving size checked. Know how many capsules the headline dose takes.
  • A real money-back guarantee. Read the checkout screen and know whether you are subscribing.
  • A conversation with your doctor. Especially if you take glucose-lowering or thyroid medication. ALA and chromium can add to the effect of glucose-lowering drugs.

The BlueOrganics Reader Offer

BlueOrganics is currently running a buy-one-get-one-free offer on its R-ALA Complex. Because metabolic support builds over weeks rather than days, two bottles is a sensible first run.

Two bottles of BlueOrganics R-ALA Complex

Optimal Health Review readers get:

  • Buy 1, get 1 free on the R-ALA Complex, two bottles for the price of one
  • All three pathways in one formula: 1,200 mg R-ALA, 1,200 mg Ceylon cinnamon and 1,000 mcg chromium picolinate
  • Every dose printed on the label, with no proprietary blend
  • A 30-day money-back guarantee. Email your order number for a full refund, no return required, keep the bottle
Check availability →

30-Day Money-Back Guarantee · Buy 1, Get 1 Free · Made in USA

What To Do With This

Healthy blood sugar runs on three pathways. Most prescriptions address one, by design, and they do it well. Most supplements address one, and several of the most popular ones do not tell you the form or the amount of what is inside.

We are not telling anyone to discontinue a medication. Your metformin is doing its job. Your glucose-lowering prescription is bringing the number down. Keep taking them, and tell your prescribing doctor before you add anything, particularly alpha-lipoic acid or chromium, which can add to the effect of those drugs.

Then ask the question this article was written around.

Bring it to your next appointment. Ask what is being done about cellular energy, insulin action and your vitamin B12. Use those words.

Watch what happens to the pace of the conversation.

BlueOrganics Liposomal R-ALA Complex Is Our #1 Blood Sugar Formula of 2026
Pathway CoverageA+
Form SpecifiedA+
Dose DisclosureA+
Delivery StatedA

Of every treatment reviewed, the most common glucose-lowering prescriptions and the bestselling blood sugar and R-ALA supplements on the American market, BlueOrganics was the only formula that covered all three pathways, named the form of every ingredient and printed every dose on the label.

Shop now
Made in
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Master Score Matrix

#1 BlueOrganics R-ALA ComplexA+
Total 9.7 / 10
Pathway coverage
9.8
Form specified
9.9
Dose disclosure
9.8
Delivery stated
9.4
#2 PrescriptionsC
Total 6.0 / 10
Clinical evidence
9.8
Pathway coverage
5.0
Side-effect profile
4.5
Nutrient impact
4.5
#3 Sunergetic Blood Sugar SupportD+
Total 4.6 / 10
Pathway coverage
7.5
Form specified
4.0
Dose disclosure
3.0
Delivery stated
4.0
#4 Noverly R-Alpha Lipoic AcidD
Total 4.0 / 10
Pathway coverage
2.5
Form specified
6.5
Dose disclosure
4.5
Delivery stated
3.0
#5 Pure Encapsulations Alpha Lipoic AcidD−
Total 3.6 / 10
Pathway coverage
2.5
Form specified
2.0
Dose disclosure
6.0
Delivery stated
2.5

Citations

  1. Centers for Disease Control and Prevention. Prediabetes: Your Chance to Prevent Type 2 Diabetes. National Diabetes Statistics Report.
  2. Reed LJ, DeBusk BG, Gunsalus IC, Hornberger CS Jr. Crystalline alpha-lipoic acid: a catalytic agent associated with pyruvate dehydrogenase. Science. 1951;114(2952):93–94.
  3. Shay KP, Moreau RF, Smith EJ, Smith AR, Hagen TM. Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential. Biochim Biophys Acta. 2009;1790(10):1149–1160.
  4. European Food Safety Authority. Coumarin in flavourings and other food ingredients with flavouring properties. EFSA Journal. 2008;793:1–15.
  5. Wang YH, Avula B, Nanayakkara NP, Zhao J, Khan IA. Cassia cinnamon as a source of coumarin in cinnamon-flavored food and food supplements in the United States. J Agric Food Chem. 2013;61(18):4470–4476.
  6. National Institutes of Health, Office of Dietary Supplements. Chromium: Fact Sheet for Health Professionals.
  7. Carlson DA, Smith AR, Fischer SJ, Young KL, Packer L. The plasma pharmacokinetics of R-(+)-lipoic acid administered as sodium R-(+)-lipoate to healthy human subjects. Altern Med Rev. 2007;12(4):343–351.
  8. American Diabetes Association. Pharmacologic Approaches to Glycemic Treatment: Standards of Care in Diabetes (vitamin B12 monitoring with long-term metformin use).
  9. Allen RW, Schwartzman E, Baker WL, Coleman CI, Phung OJ. Cinnamon use in type 2 diabetes: an updated systematic review and meta-analysis. Ann Fam Med. 2013;11(5):452–459.
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